Thursday, April 25, 2013

New Nobel letters reveal secrets of DNA prize

Heritage Auctions

Doctor Francis Crick's endorsement of the Nobel Prize check.

By Stephanie Pappas
LiveScience

A new cache of letters released 50 years after Maurice Wilkins, Francis Crick and James Watson won the Nobel Prize for the discovery of DNA's structure reveals that not everyone agreed on which prize the trio should receive.

Wilkins, Crick and Watson ended up winning the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material," according to the official citation. But at least one scientist nominated them for the chemistry prize instead, researchers will report Wednesday?in the journal Nature.

Nature first published a series of three papers describing the structure of DNA by the team on April 25, 1953, making this year the 60th anniversary of the discovery. Watson, Crick, Wilkins and Rosalind Franklin (who died before the 1962 Nobel Prize was awarded) and their colleagues were the first to understand DNA's unique double-helix structure. [Photos: Crick DNA Nobel On the Auction Block]

Nobel Prize puzzler
Jan Witkowski and Alexander Gann of Cold Spring Harbor Laboratory in New York wrote to the Nobel committee to request the release of the nomination letters for the 1962 prize, as nomination letters are unsealed after 50 years. To their surprise, one letter seemed to be missing: That of Jacque Monod, a French biologist who would later win the Nobel Prize himself for research into the genetics of enzymes.

"We were surprised because both Jim Watson and Francis Crick said that Monod was one of the people who nominated them," Witkowski told LiveScience. In fact, in 1961, Crick sent Monod a nine-page letter telling the story of the DNA structure discovery, at Monod's request.

Monod worked at the Pasteur Institute in Paris, so Witkowski and Gann turned to the Institute's archives to solve the puzzle of the missing nomination. There, they found Monod's nomination letter ? only sent to an unexpected address.

"It turns out that he nominated them for the chemistry prize, and not the medicine prize," Witkowski said. That's why the medicine or physiology committee had no record of the nomination, though the committees must have shared the nomination letters to decide which of the two prizes the DNA structure scientists should win.?

Third nominee
The nomination letters also reveal that Franklin, who died in 1958, was never nominated for the Nobel Prize. There has been a lot of controversy over whether Franklin would have shared in the Nobel had she been alive in 1962, Witkowski said. (Nobels are not awarded posthumously.) Many have argued that Franklin's contributions were downplayed and overlooked by Watson and Crick.

As it turns out, Franklin died two years before the DNA structure was first nominated for the Nobel, which occurred in 1960. Wilkins, who did early work on DNA structure, was also not a major contender from the nominators' perspectives; of six nominations, not including Monod's, only one included Wilkins. Two others suggested that the committee might possibly include him, but didn't make a case for it. In his letter to Monod, Crick was insistent Wilkins should be nominated, however.

"It could be that the nomination Monod wrote, following Crick's advice, where he strongly endorsed Wilkins may have helped sway the committee," Witkowski said.

Another series of letters, these consisting of personal correspondence released in 2010, reveal that despite this nomination congeniality, there were professional rivalries between Watson and Crick and Wilkins ? not to mention sexist attitudes toward Franklin. Another letter from Crick to his son explaining DNA went for a whopping $6 million?at auction earlier this month.

Follow Stephanie Pappas on Twitter?and Google+. Follow us @livescience, Facebook?and Google+. Original article on LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2b20e360/l/0Lscience0Bnbcnews0N0C0Inews0C20A130C0A40C240C178988780Enew0Enobel0Eletters0Ereveal0Esecrets0Eof0Edna0Eprize0Dlite/story01.htm

black friday How long to cook a turkey green bean casserole green bean casserole recipe red dawn sweet potato pie sweet potato pie

Jupiter's atmosphere still contains water supplied by the Shoemaker-Levy 9 comet impact

Apr. 23, 2013 ? Astronomy & Astrophysics is publishing Herschel observations of water in Jupiter's stratosphere. It is a clear remnant of the Shoemaker-Levy 9 comet impact on Jupiter nearly 20 years ago.

In July 1994, the comet Shoemaker-Levy 9 (SL9) hit Jupiter and left visible scars on the Jovian disk for weeks. This spectacular event was the first direct observation of an extraterrestrial collision in the solar system, and it was followed worldwide by professional and amateur astronomers.

SL9 was discovered orbiting Jupiter by astronomers David Levy and Carolyn and Eugene M. Shoemaker on March 24, 1993. It was the first comet observed orbiting a planet rather than the Sun. SL9 was found to be composed of 21 fragments. Soon after that, orbital studies showed that the comet had passed within Jupiter's Roche limit in July 1992. Inside this limit, the planet's tidal forces are strong enough to disintegrate a body held together by its own gravity, thus explaining SL9's fragmentation. Even more interestingly, the studies showed that SL9's orbit would pass within Jupiter in July 1994 and that the comet would then collide with the planet, with impacts in the southern hemisphere near 44?S latitude.

The SL9 impact and its subsequent scars on Jupiter were observed for weeks, but its chemical impact on Jupiter's atmosphere lasted even longer. Emission from water vapor was observed during the fireball phase of the SL9 impacts, but from that observation, it was difficult to assess how this would modify Jupiter's composition on the long term. In 1997, the ESA Infrared Space Observatory (ISO) detected water vapor in the stratosphere of Jupiter. At that time, astronomers suspected that it might be a consequence of the SL9 impact because comets are known to be water-rich bodies. However, there were other possible sources of water: interplanetary dust particles produced by cometary activity and asteroid collisions, icy rings, or one of the 60 Jovian satellites.

Nearly twenty years after this major impact, astronomers are still observing its consequences on Jupiter. T. Cavali? and his colleagues [1] observed Jupiter with the ESA Herschel Space Observatory, which is sensitive enough to map the abundance of water vs. latitude and altitude in the Jovian stratosphere. These observations, which have now been published in Astronomy & Astrophysics, show a clear north-south asymmetry in the distribution of water, with more water in the south. They indicate that 95% of the water currently observed on Jupiter comes from the comet.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Astronomy & Astrophysics.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. T. Cavali?, H. Feuchtgruber, E. Lellouch, M. de Val-Borro, C. Jarchow, R. Moreno, P. Hartogh, G. Orton, T. K. Greathouse, F. Billebaud, M. Dobrijevic, L. M. Lara, A. Gonz?lez, H. Sagawa. Spatial distribution of water in the stratosphere of Jupiter fromHerschelHIFI and PACS observations. Astronomy & Astrophysics, 2013; 553: A21 DOI: 10.1051/0004-6361/201220797

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2013/04/130423102335.htm

world war z groundhog day Ed Koch Groundhog Day 2013 What Time Is The Superbowl Caleb Moore House of Cards

Wednesday, April 24, 2013

EE lured 318,000 customers to 4G in Q1 2013

EE draws 318,000 3 percent  of its customers to 4G, says its on track

EE's just released its Q1 2013 earnings, giving us a look at its first full quarter with 4G services. The carrier says it's on track to its goal of a million 4G customers by the end of the year, thanks to the addition or migration of 318,000 LTE customers this quarter. Despite those more profitable clients, however, total service revenue (excluding hardware sales) was down 1.5 percent for the period over last quarter, to £1.42 billion. On one hand, the number of 4G additions could be seen as disappointing considering the company's strong marketing push of the service -- though on the other, the company's only just activated numerous regions, making that one million 4G subscriber goal seem more likely than not. We'll just have to wait a bit longer to see if Brits are really in love with LTE's extra zip -- and willing to pay for it.

Filed under: , ,

Comments

Source: EE

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/ypSElsvWj_8/

atlantic city ocean city maryland Nexus 7 KDKA Pumpkin Carving Ideas Hurricane Sandy path sandy

Tuesday, April 23, 2013

Mulu Combines Content And Commerce With ?Shop This Page' Plugin

mulu platformOnline commerce still isn?t as easy as it should be. That?s because many times, consumers find something they want while browsing a publisher site online, but then have to search for and buy it elsewhere. Well, that?s a process that Los Angeles-based startup Mulu wants to change, with an ad plugin that allows users to buy the products they?re reading about directly on the page.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/3a_BFXC9W-E/

tim tebow survivor snl peter frampton Sandy Hook Elementary School Colors Cassadee Pope Victoria Soto

Suburbs now playing a key role in gun legislation

In this photo taken April 19, 2013, Lisa Inglis, 43, of Quakertown, Pa., sits in a booth at John's Plain & Fancy Diner in Quakertown, Pa. Inglis, who calls herself a liberal Republican, said the Sandy Hook massacre left her deeply ambivalent about guns and gun control, but believes the Senate should have been able to compromise on legislation. In the emotional politics of gun control, the suburbs seem to be emerging as a new sphere of influence. The Senate's defeat last week of new firearms restrictions underscored the nation's shifting demographics and a pronounced divide on the gun issue between Americans in rural areas and in the suburbs. (AP Photo/Michael Rubinkam)

In this photo taken April 19, 2013, Lisa Inglis, 43, of Quakertown, Pa., sits in a booth at John's Plain & Fancy Diner in Quakertown, Pa. Inglis, who calls herself a liberal Republican, said the Sandy Hook massacre left her deeply ambivalent about guns and gun control, but believes the Senate should have been able to compromise on legislation. In the emotional politics of gun control, the suburbs seem to be emerging as a new sphere of influence. The Senate's defeat last week of new firearms restrictions underscored the nation's shifting demographics and a pronounced divide on the gun issue between Americans in rural areas and in the suburbs. (AP Photo/Michael Rubinkam)

In this photo taken April 19, 2013, Lisa Inglis, 43, of Quakertown, Pa., sits in a booth at John's Plain & Fancy Diner in Quakertown, Pa. Inglis, who calls herself a liberal Republican, said the Sandy Hook massacre left her deeply ambivalent about guns and gun control, but believes the Senate should have been able to compromise on legislation. In the emotional politics of gun control, the suburbs seem to be emerging as a new sphere of influence. The Senate's defeat last week of new firearms restrictions underscored the nation's shifting demographics and a pronounced divide on the gun issue between Americans in rural areas and in the suburbs. (AP Photo/Michael Rubinkam)

(AP) ? In the emotional politics of gun control, the suburbs seem to be emerging as a new sphere of influence.

The Senate's defeat last week of firearms restrictions underscored the nation's shifting demographics and a pronounced divide on the gun issue between Americans in rural areas and residents of suburban enclaves, like Quakertown, outside Philadelphia.

Packed with married women and political independents, vote-rich communities like these are starting ? in the wake of a string of shooting massacres ? to act more like urban centers that long have been concerned with the threat of local gun violence and have favored stricter laws. Those include the expansion of background checks, viewed by gun control advocates as a way to prevent criminals and the mentally ill from buying firearms.

Like most Pennsylvania voters, Lisa Inglis, 43, a stay-at-home mom of two from the Philadelphia suburbs, is a supporter of expanded checks of gun buyers, part of the legislation defeated last week. She said she was very disappointed by the Senate action, though she also questioned whether such measures would prevent many crimes.

"The reality hits you that nobody can keep anybody safe. You really depend on the stability of other people's thinking. You just hope for the best," said Inglis, eating at John's Plain & Fancy Diner in Quakertown, about 45 miles north of Philadelphia.

Voters like her in suburbs like this are a big reason why a handful of Republican lawmakers broke ranks with the GOP last week to support the expanded checks, raising the possibility that gun control could end up becoming more acceptable to other Republicans as suburbs in swing-voting states swell and push farther into rural areas where people cherish their gun rights.

Four Republicans backed the proposal, including three ? Sens. Patrick Toomey of Pennsylvania, Mark Kirk of Illinois and John McCain of Arizona ? where suburbs play a strong role in their home states' politics. The proposal also won support from Democrats such as Virginia Sens. Mark Warner and Tim Kaine and Colorado Sens. Michael Bennet and Mark Udall, two states that are home to many hunters living in rural areas ? but also to booming suburbs outside Washington and Denver.

To be sure, rural interests still play a powerful role in Congress, and the gun vote showed how small states can shape the debate. Democrats representing rural states bucked members of their party and President Barack Obama to help scuttle the legislation. Among Democrats, five opposed the plan, including rural state lawmakers like Mark Pryor of Arkansas, Mark Begich of Alaska and Max Baucus of Montana, all of whom face the voters next year.

Polling bears out the geographic divide.

In the months since the deadly Newtown, Conn., elementary school shooting, polls showed an overwhelming support for expanding background checks and strong sentiment for tighter gun measures among women. An Associated Press-GfK poll this month found that 52 percent of people living in suburban areas supported stricter gun laws compared with 41 percent rural residents. An additional 44 percent who live in rural areas say gun laws should remain the same, 13 percent think they should be made less strict.

The poll found that 58 percent of women favored stricter gun laws, compared with 41 percent of men. The difference held up across party lines, though 34 percent of Republican women supported stricter gun laws compared with 80 percent of Democratic women.

Republicans said many GOP members were challenged by the larger context of Obama's agenda ? including likely votes ahead on immigration and growing support in the nation for gay marriage. "They can't go all in. They have to pick and choose," said Chip Felkel, a South Carolina-based Republican strategist. "The NRA doesn't want to give an inch on anything because they think it's the beginning of the slide."

Toomey's role offered an apt case study. A reliable conservative and former head of the free-market advocacy group Club for Growth, Toomey joined forces with West Virginia Democrat Joe Manchin to push for expanded background checks. Toomey has garnered strong ratings from the National Rifle Association but faces re-election in 2016, a presidential year in which elections in his home state tend to pivot on voters in the Philadelphia and Pittsburgh suburbs.

Inglis, of Quakertown, calls herself a "liberal Republican" ? she voted for Obama twice and Toomey in 2010 ? and she credited Toomey with picking "the right issue to break out of his mold on." She said it made her view him as a pragmatist working to solve problems.

Bob Linquist, 73, a retired utility worker from Quakertown, used to belong to the NRA but dropped his membership because of the group's views on military-style assault weapons, which he believes do not belong in private hands. Linquist, a Democrat who sometimes votes Republican, said he supported Toomey's position on background checks even though he questioned whether it would solve the problem and thought it was politically calculated.

"Politicians don't always stand up for their country or ideologically what's right or morally right. They worry about their job," Linquist said.

Toomey sought to explain his position to a gathering of conservatives during the weekend. "My hope is that we can agree to disagree on this and move on to the many, many areas on which we agree," he told the Pennsylvania Leadership Conference in Camp Hill.

Terry Madonna, a pollster and political scientist at Franklin & Marshall College, said that with more than 9 in 10 Pennsylvanians supporting universal background checks, Toomey staked out a very safe political position. He said Toomey's bill was probably designed to appeal to swing voters in suburban Philadelphia, noting that "the largest area of support for gun control measures comes from the Philly suburbs."

The pressure points on the bill were found in the suburbs. A gun-control group backed by New York Mayor Michael Bloomberg focused its persuasion campaign ? with mixed results ? on areas represented by Republicans that include pivotal suburbs. The organization, Mayors Against Illegal Guns, aired ads in Philadelphia, Phoenix, Atlanta, Las Vegas and parts of Ohio.

Despite the measure's failure, some Democrats view it as evidence of how the issue has taken hold of suburban voters.

"Pat Toomey is no moderate. The fact that he's doing it in the state he's from tells you the power of the suburbs," said Rep. Gerald Connolly, D-Va., who represents a suburban district outside Washington.

___

Thomas reported from Washington.

___

Follow Ken Thomas http://twitter.com/AP_Ken_Thomas and Michael Rubinkam on Twitter: http://twitter.com/MichaelRubinkam

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-22-Gun%20Politics%201st%20Ld-Writethru/id-9de22b3f2ce94c55af80d15f52ddc6ce

miami marlins marlins marlins facebook buys instagram kevin systrom fibonacci sequence maryland lottery

Woman unknowingly takes 30 pounds of pot across U.S.-Mexico border

Bricks of confiscated marijuana (Getty Images)

This is awkward. A woman who lives in Mexico and works in San Diego called the cops on herself when she apparently unknowingly transported 30 pounds of marijuana across the border.

According to a report by NBC New York, the unnamed 33-year-old drove her car to work Friday morning, arrived early and was sitting in her car in a parking lot around 4 a.m. when two unidentified men approached her car and began removing packages from underneath it.

The driver surprised the men, who got in their car and drove off. She called the police, who discovered 30 pounds of pot divided into six packages attached by heavy-duty magnets to the undercarriage of the vehicle.

Who put the drugs there?the woman said it wasn?t her?remains a mystery. Police tell NBC New York that no arrests have been made.

Officials want to remind people who regularly cross the border to check their car?as some people become targets by drug cartels as unwitting mules in the narcotics business.

Regular border travelers may be a boon to drug smugglers.

Last year, CNN reported a similar story of a
regular commuter from his home in Ciudad Juarez, Mexico, to the University of Texas at El Paso.

Even though the man, who goes under a fake name to protect his identity, said he was targeted and ferried drugs without his knowledge, he was sentenced to six months in prison.

Source: http://news.yahoo.com/blogs/sideshow/woman-unknowingly-takes-30-pounds-pot-across-u-144432116.html

george zimmerman website edmund fitzgerald uss enterprise white house easter egg roll 2012 andy cohen andy cohen mozambique

T-Mobile website, computer systems down over the weekend

T-Mobile SIM

High demand to blame for the outages; wireless network was not affected

If you had trouble accessing the T-Mobile website over the weekend, you weren't the only one. Not only were other customers having issues with the site, but also customer service reps in stores trying to operate internal computers. The sporadic outage, which seemed to take place for most of Saturday, was confirmed today by T-Mobile. In a statement to FierceWireless, the carrier said the issues were the result of extremely high demand -- with no further elaboration provided.

With the launching of a completely new plan and carrier strategy, along with some high profile device launches, it's not surprising that T-Mobile's website was under some serious pressure in the last couple of days. While the carrier thanks customers for their patience with the issue, it says that an apology is in order for the services being temporarily unavailable. It has also been confirmed that the wireless network did not experience outages over the same period.

Source: FierceWireless

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/f7tYCAH3KO4/story01.htm

vcu mario williams unlv sam young ramon sessions portland trail blazers blagojevich