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Public release date: 13-Feb-2013
Share ] Contact: Mary Leach
mary_leach@meei.harvard.edu
617-573-4170
Massachusetts Eye and Ear Infirmary
Boston (Feb. 13, 2013)--Joan Whitten Miller, M.D., Henry Willard Williams Professor of Ophthalmology and Chair of Ophthalmology at Harvard Medical School, and Chief of Ophthalmology at Massachusetts Eye and Ear Infirmary and Massachusetts General Hospital, has been elected to the Academia Ophthalmologica Internationalis (AOI).
The AOI is regarded as the most prestigious international academic organization in ophthalmology with an emeritus and active membership that spans 33 countries.
Dr. Miller is only the second American woman to be elected to the 38-year-old organization, which limits active membership to 70 individuals.
As a university-centered organization, the AOI is "committed to excellence in education, research and culturally appropriate medical services to preserve and restore vision for people of the world."
The AOI counts among its membership some of the most acclaimed ophthalmologists worldwide, including: David W. Parke II, M.D., President of the American Academy of Ophthalmology; Martine J. Jager, M.D., past President of the Association for Vision in Research and Ophthalmology; Alfred Sommer, M.D., M.H.S., Board of Directors Chair of the Albert and Mary Lasker Foundation; and Paul R. Lichter, M.D., M.S., current AOI President.
"It's truly humbling to be in the company of such an elite group of academicians, all of whom have dedicated their careers to shifting the landscape of eye health around the globe," noted Dr. Miller. "I'm excited and honored to contribute my expertise to AOI's global mission to bring hope and sight to people around the world."
The AOI originated with the Act of Foundation signed March 7, 1975, and its statutes and regulations were approved on April 10, 1976 by a vote from 45 Charter Members at the inaugural meeting in Ghent, Belgium.
Eligible candidates who meet the Academia's high standards of scholarly excellence are formally nominated and elected by other members to fill vacant chairs. Members are expected to actively engage in improving world ophthalmology.
"This is among the highest honors conferred in the field of ophthalmology and is a fitting tribute to Dr. Miller and her astonishingly productive career." said President and CEO of Mass. Eye and Ear, John Fernandez. "Her contributions to the field of ophthalmology have turned the tide on some of our most egregious battles in the war on blindness, particularly in the field of angiogenesis and age-related macular degeneration (AMD). We consider ourselves very fortunate to have her a clinician and scientist of the highest caliber - leading our efforts here at Mass. Eye and Ear.
"Dr. Miller has pushed the frontiers of understanding to improve the lives of patients," said HMS Dean Jeffrey S. Flier. "I am pleased that the AOI has recognized Dr. Miller's leadership in translational research, which is central to the mission of Harvard Medical School."
Over the last two decades, Dr. Miller and her colleagues at Harvard Medical School/Mass. Eye and Ear pioneered the development of photodynamic therapy (PDT) using verteporfin (Visudyne), the first pharmacologic therapy for AMD able to reduce and slow vision loss. The group also identified the importance of vascular endothelial growth factor (VEGF) in ocular neovascularization, forming the scientific basis of current antiangiogenic therapies for neovascular AMD.
Today, these treatments are saving the sight of millions of people worldwide. Dr. Miller and her colleagues continue investigations to elucidate the molecular pathophysiology of vision loss and develop improved therapies for retinal disease. Dr. Miller's current clinical and research interests focus on retinal disorders, including age-related macular degeneration (AMD) and diabetic retinopathy.
Dr. Miller has published more than 130 peer-reviewed papers, 50 book chapters and review articles, is co-editor of the third edition of Albert and Jakobiec's Principles and Practice of Ophthalmology, and is a named inventor on nine U.S. patents and five Canadian patents. She has received numerous awards, including the Rosenthal Award and Donald J. Gass Medal of the Macula Society, the Retina Research Award from the Club Jules Gonin, the Alcon Research Institute Award, the ARVO/Pfizer Ophthalmic Translational Research Award, the Founder's Award from the American Society of Retinal Specialists, the Suzanne Veronneau-Troutman Award from Women in Ophthalmology, the Paul Henkind Memorial Award from the Macula Society, the Senior Achievement Award from the American Academy of Ophthalmology, and the Certificate of Honour from the European Association for Vision and Eye Research.
Dr. Miller was born in Toronto, Ontario, Canada and is a graduate of Massachusetts Institute of Technology and Harvard Medical School. She completed her ophthalmology residency and a vitreo-retinal fellowship at Mass. Eye and Ear. In addition to her professorship and leadership roles at Harvard Medical School and Mass. Eye and Ear, Dr. Miller is the director of the Angiogenesis Laboratory and a vitreo-retinal physician in the Retina Service at Mass. Eye and Ear.
She is the first female physician promoted to the rank of Professor of Ophthalmology at Harvard Medical School, and the first woman to serve as chair of the Department of Ophthalmology.
Dr. Miller and her husband John live in Winchester, MA. John, a construction attorney, specializes in domestic and international engineering procurement and public-private partnerships in global infrastructure. The eldest of three children, their son John is currently an ophthalmology resident at Harvard Medical School. Their son Douglas is a 2010 graduate of Harvard College, where he was co-captain of his college basketball team; he now works in construction management for Schernecker Property Services. Daughter Mary graduated from Harvard College in 2011, and is working as a paralegal for the law firm Harkins Cunningham LLP in Philadelphia.
###
About Massachusetts Eye and Ear
Mass. Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck. After uniting with Schepens Eye Research Institute in 2011, Mass. Eye and Ear in Boston became the world's largest vision and hearing research center, offering hope and healing to patients everywhere through discovery and innovation. Mass. Eye and Ear is a Harvard Medical School teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships. Internationally acclaimed since its founding in 1824, Mass. Eye and Ear employs full-time, board-certified physicians who offer high-quality and affordable specialty care that ranges from the routine to the very complex. U.S. News & World Report's "Best Hospitals Survey" has consistently ranked the Mass. Eye and Ear Departments of Otolaryngology and Ophthalmology as top five in the nation. For more information about life-changing care and research, or to learn how you can help, please visit MassEyeAndEar.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 13-Feb-2013 Share ] Contact: Mary Leach
mary_leach@meei.harvard.edu
617-573-4170
Massachusetts Eye and Ear Infirmary
Boston (Feb. 13, 2013)--Joan Whitten Miller, M.D., Henry Willard Williams Professor of Ophthalmology and Chair of Ophthalmology at Harvard Medical School, and Chief of Ophthalmology at Massachusetts Eye and Ear Infirmary and Massachusetts General Hospital, has been elected to the Academia Ophthalmologica Internationalis (AOI).
The AOI is regarded as the most prestigious international academic organization in ophthalmology with an emeritus and active membership that spans 33 countries.
Dr. Miller is only the second American woman to be elected to the 38-year-old organization, which limits active membership to 70 individuals.
As a university-centered organization, the AOI is "committed to excellence in education, research and culturally appropriate medical services to preserve and restore vision for people of the world."
The AOI counts among its membership some of the most acclaimed ophthalmologists worldwide, including: David W. Parke II, M.D., President of the American Academy of Ophthalmology; Martine J. Jager, M.D., past President of the Association for Vision in Research and Ophthalmology; Alfred Sommer, M.D., M.H.S., Board of Directors Chair of the Albert and Mary Lasker Foundation; and Paul R. Lichter, M.D., M.S., current AOI President.
"It's truly humbling to be in the company of such an elite group of academicians, all of whom have dedicated their careers to shifting the landscape of eye health around the globe," noted Dr. Miller. "I'm excited and honored to contribute my expertise to AOI's global mission to bring hope and sight to people around the world."
The AOI originated with the Act of Foundation signed March 7, 1975, and its statutes and regulations were approved on April 10, 1976 by a vote from 45 Charter Members at the inaugural meeting in Ghent, Belgium.
Eligible candidates who meet the Academia's high standards of scholarly excellence are formally nominated and elected by other members to fill vacant chairs. Members are expected to actively engage in improving world ophthalmology.
"This is among the highest honors conferred in the field of ophthalmology and is a fitting tribute to Dr. Miller and her astonishingly productive career." said President and CEO of Mass. Eye and Ear, John Fernandez. "Her contributions to the field of ophthalmology have turned the tide on some of our most egregious battles in the war on blindness, particularly in the field of angiogenesis and age-related macular degeneration (AMD). We consider ourselves very fortunate to have her a clinician and scientist of the highest caliber - leading our efforts here at Mass. Eye and Ear.
"Dr. Miller has pushed the frontiers of understanding to improve the lives of patients," said HMS Dean Jeffrey S. Flier. "I am pleased that the AOI has recognized Dr. Miller's leadership in translational research, which is central to the mission of Harvard Medical School."
Over the last two decades, Dr. Miller and her colleagues at Harvard Medical School/Mass. Eye and Ear pioneered the development of photodynamic therapy (PDT) using verteporfin (Visudyne), the first pharmacologic therapy for AMD able to reduce and slow vision loss. The group also identified the importance of vascular endothelial growth factor (VEGF) in ocular neovascularization, forming the scientific basis of current antiangiogenic therapies for neovascular AMD.
Today, these treatments are saving the sight of millions of people worldwide. Dr. Miller and her colleagues continue investigations to elucidate the molecular pathophysiology of vision loss and develop improved therapies for retinal disease. Dr. Miller's current clinical and research interests focus on retinal disorders, including age-related macular degeneration (AMD) and diabetic retinopathy.
Dr. Miller has published more than 130 peer-reviewed papers, 50 book chapters and review articles, is co-editor of the third edition of Albert and Jakobiec's Principles and Practice of Ophthalmology, and is a named inventor on nine U.S. patents and five Canadian patents. She has received numerous awards, including the Rosenthal Award and Donald J. Gass Medal of the Macula Society, the Retina Research Award from the Club Jules Gonin, the Alcon Research Institute Award, the ARVO/Pfizer Ophthalmic Translational Research Award, the Founder's Award from the American Society of Retinal Specialists, the Suzanne Veronneau-Troutman Award from Women in Ophthalmology, the Paul Henkind Memorial Award from the Macula Society, the Senior Achievement Award from the American Academy of Ophthalmology, and the Certificate of Honour from the European Association for Vision and Eye Research.
Dr. Miller was born in Toronto, Ontario, Canada and is a graduate of Massachusetts Institute of Technology and Harvard Medical School. She completed her ophthalmology residency and a vitreo-retinal fellowship at Mass. Eye and Ear. In addition to her professorship and leadership roles at Harvard Medical School and Mass. Eye and Ear, Dr. Miller is the director of the Angiogenesis Laboratory and a vitreo-retinal physician in the Retina Service at Mass. Eye and Ear.
She is the first female physician promoted to the rank of Professor of Ophthalmology at Harvard Medical School, and the first woman to serve as chair of the Department of Ophthalmology.
Dr. Miller and her husband John live in Winchester, MA. John, a construction attorney, specializes in domestic and international engineering procurement and public-private partnerships in global infrastructure. The eldest of three children, their son John is currently an ophthalmology resident at Harvard Medical School. Their son Douglas is a 2010 graduate of Harvard College, where he was co-captain of his college basketball team; he now works in construction management for Schernecker Property Services. Daughter Mary graduated from Harvard College in 2011, and is working as a paralegal for the law firm Harkins Cunningham LLP in Philadelphia.
###
About Massachusetts Eye and Ear
Mass. Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck. After uniting with Schepens Eye Research Institute in 2011, Mass. Eye and Ear in Boston became the world's largest vision and hearing research center, offering hope and healing to patients everywhere through discovery and innovation. Mass. Eye and Ear is a Harvard Medical School teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships. Internationally acclaimed since its founding in 1824, Mass. Eye and Ear employs full-time, board-certified physicians who offer high-quality and affordable specialty care that ranges from the routine to the very complex. U.S. News & World Report's "Best Hospitals Survey" has consistently ranked the Mass. Eye and Ear Departments of Otolaryngology and Ophthalmology as top five in the nation. For more information about life-changing care and research, or to learn how you can help, please visit MassEyeAndEar.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-02/meae-jwm021313.php
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WASHINGTON (AP) ? The Senate Intelligence Committee will delay voting to confirm John Brennan as CIA director as the panel's Democratic chairwoman demanded Wednesday that the White House turn over more details about lethal drone strikes on terror suspects and last September's attack in Benghazi, Libya, that left the U.S. ambassador there and three other Americans dead.
Intelligence Chairwoman Dianne Feinstein said the vote likely will be pushed off until late February.
In a statement, the California Democrat said senators need to see more classified legal opinions that justify using the unmanned spy planes to kill al-Qaida suspects overseas, including American citizens. The Obama administration last week released two of nine classified Justice Department memos outlining the legal reasoning to Feinstein's committee just hours before Brennan's confirmation hearing in front of the panel.
Feinstein said the memos are necessary "in order to fully evaluate the executive branch's legal reasoning, and to broaden access to the opinions to appropriate members of the committee staff."
The White House declined to comment Wednesday.
Feinstein and other lawmakers are considering creating a special court to review strikes against U.S. citizens. In 2011, drone strikes in Yemen killed three Americans: U.S. born cleric Anwar al-Awlaki, his 16-year-old-son and al-Qaida propagandist Samir Khan.
Last week, Brennan defended the strikes in his confirmation testimony, but also said he welcomed more discussion on the controversial program.
"American citizens by definition are due much greater due process than anybody else by dint of their citizenship," Brennan told Feinstein's committee.
The Senate and House Judiciary committees also want to see the documents, and other lawmakers are pressing the White House for more for information on the Sept. 11 attack on a U.S. diplomatic post in Benghazi the killed Ambassador Chris Stevens.
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(Reuters) - You survived December's much-heralded Mayan apocalypse, but now fear the "zombie apocalypse" and its deadly attacks? Don't worry. It was a fake, the artwork of hackers in Montana.
Hackers infiltrated the emergency broadcast system of local station KRTV in Great Falls, Montana, a CBS affiliate, and issued the zombie alert, the station said on Tuesday.
Viewers were warned of a so-called zombie apocalypse and advised not to tangle with the monstrous creatures, the station said.
Engineers at the station were investigating the incident, which occurred during a Monday afternoon broadcast, said Jon Saunders, vice president of the station's parent company, Cordillera Communications.
Video posted to the Internet shows the transmission interrupted a local broadcast of the Steve Wilkos talk show.
No images flashed across the screen during the hoax. But a male voice told viewers: "Civil authorities in your area have reported that the bodies of the dead are rising from the grave and attacking the living." The voice warned not "to approach or apprehend these bodies as they are extremely dangerous."
Saunders said early reports suggest similar but separate attacks were launched in the past 24 hours against emergency alert systems for TV stations elsewhere, including Michigan.
"It appears to be more widespread than we thought," he said.
The hoax caused several humorous-minded residents in Great Falls to call authorities to inquire if guns were an adequate defence against zombie hordes.
"We didn't get any serious calls on it," Great Falls Police Department spokesman Bill Hunter said.
Local law enforcement has not been asked to investigate the hack into the Montana station, he said. Hunter said it was not immediately clear why hackers had sought to get a rise out of a zombie scare.
"It's been a real chuckle," he said.
(Editing by Alex Dobuzinskis, Cynthia Johnston and Leslie Adler)
Source: http://news.yahoo.com/zombie-apocalypse-warning-montana-fake-222206285.html
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Feb. 8, 2013 ? Every year, sensors designed to detect nuclear explosions see harmless bursts in Earth's upper atmosphere from the breakup of an asteroid a few yards across. Tiny asteroids are much more numerous than big ones, so destructive hits to Earth are very rare. However, because of their potential for devastation, NASA's Near-Earth Object (NEO) observations program supports surveys which are undertaking sustained searches to find the largest objects and predict their impact threat to Earth.
According to NASA's NEO program, there are more than 1,300 "Potentially Hazardous Asteroids" (PHAs) -- objects at least 150 yards (about 140 meters) across with a very small chance of impacting us someday because their orbital paths take them close to Earth's orbit.
"Asteroids move at an average of 12 to 15 kilometers per second (about 27,000 to 33,000 miles per hour) relative to Earth, so fast that they carry enormous energy by virtue of their velocity," says Edward Beshore of the University of Arizona, Tucson, deputy principal investigator for NASA's OSIRIS-REx asteroid sample return mission. "Anything over a few hundred yards across that appears to be on a collision course with Earth is very worrisome."
The main difficulty is obtaining sufficient observations to be able to predict their orbits with enough certainty to find out if they could hit us at some point.
"When an asteroid makes a close pass to Earth, the gravitational pull from our planet changes the asteroid's orbit," says Beshore. "However, how this change will affect the evolution of the asteroid's orbit is difficult for us to predict because there are also other small forces continuously acting on the asteroid to change its orbit. The most significant of these smaller forces is the Yarkovsky effect -- a minute push on an asteroid that happens when it is warmed up by the sun and then later re-radiates this heat in a different direction as infrared radiation."
The Yarkovsky effect happens simply because it takes time for things to heat up and cool down. Objects tend to be coldest just before dawn and warmest at mid-afternoon, after hours of illumination by the high sun. "A brick building can feel warm even in the early evening hours, because it is radiating away the heat accumulated from an entire day of sunshine," says Beshore. In the same way, an asteroid radiates most of its heat from its late "afternoon side," giving it the small Yarkovsky push which is variable depending mostly on the asteroid's size, shape and composition.
NASA's OSIRIS-REx mission (Origins, Spectral Interpretation, Resource Identification, Security, and Regolith Explorer) will make the most precise measurements of the Yarkovsky effect to date by visiting a PHA called "1999 RQ36" or just "RQ36."
"For such a large object, it has one of the highest known probabilities of impacting Earth, a 1 in 2,400 chance late in the 22nd century, according to calculations by Steve Chesley, an astronomer at NASA's Jet Propulsion Laboratory," said Beshore. RQ36 is about 457 meters (500 yards) across.
The best measurements of the Yarkovsky effect are made when an asteroid's position is precisely known. "If an asteroid comes very close, we can get radar observations on it," says Beshore. "With radar measurements, we get very good data on its range and therefore can constrain one aspect of its orbit very well. If we can get that measurement a couple of times (or more) over a few years, it helps us understand its orbital behavior and we can start to make an estimate of the Yarkovsky effect. We estimate the position of the asteroid and what its orbit must be like by using Newtonian and Relativistic physics. If we see a deviation from the estimated position, then it must be due to the sum of all these other small forces, and the greatest of these we believe to be the Yarkovsky effect."
Measurements like these enabled the team to estimate the very small force of the Yarkovsky effect on RQ36 -- about equal to the weight felt when holding three grapes, according to Beshore. "Although very small, this force is constant and adds up over time to significantly change the asteroid's orbit," adds Beshore.
Scheduled for launch in 2016, OSIRIS-REx will arrive at RQ36 in 2018 and orbit the asteroid until 2021. By communicating continuously with a spacecraft in orbit around RQ36, the team will get a much better idea of the asteroid's orbit.
"We expect OSIRIS-REx will enable us to make an estimate of the Yarkovsky force on RQ36 at least twice as precise as what's available now," says Jason Dworkin, OSIRIS-REx project scientist at NASA's Goddard Space Flight Center in Greenbelt, Md.
The team will use what it learns about the Yarkovsky effect on RQ36 to help estimate the effects on other asteroids. "What we want to be able to do is create a model that says okay if you give me an asteroid of this size, made of this composition, with this kind of topography, I can estimate for you what the Yarkovsky effect will be," says Beshore. "So now I can probably come up with a better notion of what to expect from other asteroids that I don't have the good fortune to have a spacecraft around."
Given that OSIRIS-REx lets us better model the Yarkovsky effect, and we discover an asteroid that might hit us someday, what if anything can be done about it?
"There are several mitigation strategies," says Beshore. "We could explode a small nuclear device close above the surface on one side of the asteroid. This could be very effective -- it would vaporize the surface layer, which would then fly off at very high speed, causing a rocket thrust that would shove everything over by a few centimeters per second. This might be plenty to deflect the asteroid. Other strategies include kinetic impactors, where you strike an asteroid very hard with a heavy projectile moving at high speed. In 2005, NASA's Deep Impact mission hit comet Tempel 1 with a 370-kilogram (over 815-pound) copper slug at about five kilometers per second (over 11,000 miles per hour), not nearly enough to significantly alter the orbit of the five-kilometer-sized body, but a proof of the technology for this kind of mission. Another idea is to use a gravity tractor -- station a spacecraft precisely enough near the asteroid which would gradually deflect it with only its gravitational pull."
The key to all these strategies is to discover the asteroid well in advance of its impact date and attempt to deflect it early, according to Beshore. "If you're trying to deflect an arrow, you wouldn't need to apply much force to the arrow to make it widely miss the target if you could deflect it as it left the bow," says Beshore. "On the other hand, if you had to deflect it right before it hit the target, you'd need to push on it a whole lot more to get it out of the way."
One of the first things that would be done if an asteroid appeared to be on a collision course with Earth is to send a probe to the asteroid that might look very much like OSIRIS-REx, according to Beshore. "You want to characterize it first to choose the correct deflection strategy," says Beshore. "For example, we know the density of RQ36 is about 1 gram per cubic centimeter, over two times less than solid rock. This means it is probably a rubble pile -- a collection of boulders, rocks, and dust loosely held together by gravity. Some deflection strategies might be ineffective with this kind of asteroid."
OSIRIS-REx will determine if RQ36 is actually a rubble pile by orbiting it and revealing the subtle effects on the orbit from the gravity of any large and dense lumps within the asteroid. A probe like OSIRIS-REx could map the internal structure of an asteroid this way, providing valuable information on where to target the deflection mechanism.
OSIRIS-REx will also determine the composition of RQ36 using remote measurements from both visible light and infrared spectrometers, and by collecting a sample of material from the asteroid's surface and returning it to Earth for study. Since the Yarkovsky effect may vary depending on the type of material and its distribution, a probe with OSIRIS-REx's capability to map the surface composition will enable a more precise estimate of the Yarkovsky effect on the asteroid's orbit.
The mission will also provide critical experience navigating around asteroids. "We don't have a lot of experience doing precise maneuvers near one of these objects with very small gravity," says Beshore. "It's not easy to stay in orbit around it -- this asteroid's gravitational pull is so weak, the push from sunlight on our spacecraft's solar panels will be roughly similar to the amount of force from the gravity of RQ36 itself. We have to factor in a lot of these forces to navigate and operate around an asteroid. With OSIRIS-REx, we'll generate a set of techniques and technologies for any mission that would go to an asteroid to characterize it in advance of a mitigation mission."
The OSIRIS-REx mission is led by Principal Investigator Dante Lauretta of the University of Arizona, supported by a science team of Co-Investigators from multiple institutions, with project management at NASA's Goddard Space Flight Center, Greenbelt, Md., and development partnership with Lockheed Martin Space Systems, Littleton, Colo. International contributions are provided by the Canadian Space Agency. The OSIRIS-REx mission was selected under the NASA New Frontiers program, managed by NASA's Marshall Space Flight Center, Huntsville, Ala., and funded by NASA's Science Mission Directorate, NASA Headquarters, Washington.
More information about OSIRIS-REx can be found at: http://osiris-rex.lpl.arizona.edu/
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/BnqtUlHBYfg/130208112058.htm
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KABUL, Afghanistan (AP) ? A government official says a roadside bomb has struck a car in southern Afghanistan, killing six civilians.
The spokesman for the governor of southern Helmand province said Saturday two women and four men were killed in the blast in the Nad Ali district.
Spokesman Ahmad Zeerak says those killed were all "innocent civilians and from one family." He says they were driving home from a nearby village in their own car when the explosion occurred at about 7 p.m. Friday.
Helmand province has been the focus of several U.S.-led offensives, but it remains one of the most dangerous areas in the country.
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NEW YORK (AP) ? Katie Holmes and her business partner and stylist Jeanne Yang joined the New York Fashion Week frenzy last season with a show at Lincoln Center, only to leave it behind this time around.
It wasn't all the people, or even the paparazzi, that drove them away. It was their own clothes. Their look, which they describe as one of careful artistry and potential heritage pieces that women will keep a lifetime, is a little too quiet for all the splash, they said.
"We wanted to tell the full story behind the frivolity," said Yang, adding: "It's a quiet approach."
Holmes and Yang sat down at a hotel on the opposite side of Manhattan with a handful of fashion journalists on Thursday, the opening day of fashion week, to walk them personally through 15 looks Holmes called their favorites.
Katharine Hepburn's practical-yet-chic look of the 1940s, Donna Karan's use of the shoulders and back as erogenous zones, Halston's glamorous sportswear and Chanel's mastery of seaming and studs were all in their minds as they built the pieces and outfits.
"We're not trying to be trendy ... but we're trying to make high-quality pieces you'll wear over and over again," Holmes said.
Holmes was wearing an A-line shirtdress in the blue-and-black plaid that was dominant in the collection, while Yang wore one of the slouchy blazers that has become a key piece for the label, founded in 2009.
For fall, they'll offer a peplum top with a suede waist band and maxi skirt in the same plaid. Holmes suggested that outfit for a dinner out. Swap the shirt for a tank top for brunch and a blouse to go to the theater. Yang said she hoped a customer would "feel smart" in a white cashmere-silk boucle sweaterdress with a strip of white silk at the hem.
Holmes, meanwhile, was partial to the baggy suede caramel-colored pants that hit just above the ankle, worn with a bow-neck blouse in a deep shade of lipstick pink.
The duo made a point of noting that 70 percent of production of Holmes & Yang happens in New York and the other 30 percent in Los Angeles.
___
Follow Samantha Critchell on Twitter at http://twitter.com/AP_Fashion
Source: http://news.yahoo.com/katie-holmes-takes-fashion-line-crosstown-150250552.html
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In April of 2011, we spent some time in the driver's seat of the Tesla Roadster 2.5 Sport. Its throttle response and dashing good looks earned high marks, but the range anxiety left a bit to be desired. Now it's the winter of 2013, and in the latest issue of our weekly, we settle in behind the wheel of the Model S to determine if Tesla's refined offering has the chops to lead the EV fleet. Of course, these vehicles need a place to recharge, so Eyes-On visits one of the aforementioned outfit's Superchargers that look to make roadtrips a reality for electric vehicles. Aside from the automotive features, OUYA devs sound off on the pros and cons of the console while we put both the HP Spectre XT TouchSmart and Microsoft's Surface Pro through their respective paces. There's much more than we can pack into a single paragraph, so visit your weekly access link to grab a copy.
Distro Issue 77 PDF
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Source: http://www.engadget.com/2013/02/08/distro-issue-77-tesla-model-s/
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ZURICH (Reuters) - Credit Suisse
The Zurich-based bank said it will slash spending by 4.4 billion Swiss francs ($4.83 billion) by the end of 2015, up from a previously-announced target of 4 billion.
Fourth-quarter net profit of 397 million francs undershot analyst forecasts, which averaged 645 million francs in a Reuters poll.
Revenue and profit from Credit Suisse's investment bank slid from the third quarter, with client activity muted in both main fixed income and equity arms, the bank said.
Meanwhile, revenue and profit at the private bank, recently merged with Credit Suisse's asset management unit, rose on the year.
Thus far, Credit Suisse has been coy about how many employees it plans to let go in order to reach its spending cut target, beyond 3,500 jobs it said in November 2011 it would chop.
The bank employed 47,400 staff at the end of December, meaning it shed 1,000 employees since September.
Credit Suisse said it would pay shareholders 0.75 francs per share, of it 0.10 in cash and the remainder in shares, compared to 0.75 per share in 2011.
($1 = 0.9105 Swiss francs)
(Reporting By Katharina Bart, editing by Emma Thomasson)
Source: http://news.yahoo.com/credit-suisse-lifts-cost-cutting-goal-swings-q4-054711637--finance.html
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From Action Comics #1
Seeking to end nearly a decade of litigation, DC Comics has asked for summary judgment in lawsuits brought by the heirs of Jerry Siegel regarding the copyrights to Superman and Superboy.
In a motion filed Thursday in federal court, and first reported by Law360, the publisher?s attorneys assert the Jan. 10 ruling by the Ninth Circuit Court of Appeals that effectively affirmed DC?s ownership of the Man of Steel bars Siegel?s daughter Laura Siegel Larson from moving forward with any claims.
That decision overturned a 2008 ruling that permitted Siegel?s family to recapture his portion of the copyright to the first Superman story in Action Comics #1 under a provision of the 1976 Copyright Act, which seemingly cleared a path for the estate of his collaborator Joe Shuster to do the same this year. That would have given the family of ownership of many of the Man of Steel?s defining elements, including his origin, his secret identity, Lois Lane and certain aspects of his costume and powers (super-strength and super-speed), while leaving DC with such later additions as Lex Luthor, kryptonite and Jimmy Olsen ? not to mention the all-important trademarks.
However, that possibility was relatively short-lived: In October 2012, a federal judge found the Shuster estate?s 2003 copyright-termination notice was invalidated by a 20-year-old agreement with DC in which the late artist?s sister Jean Peavy relinquished all claims to Superman in exchange ?more than $600,000 and other benefits,? including payment of Shuster?s debts following his death earlier that year and a $25,000 annual pension for Peavy.
The Jan. 10 ruling against the Siegel heirs also came down to an earlier agreement, as the Ninth Circuit found that Larson had accepted a 2001 offer from DC that would have permitted the publisher to retain all rights to Superman (as well as Superboy and The Spectre) in exchange for $3 million in cash and contingent compensation worth tens of millions. Larson insisted she never formally accepted the offer, freeing her and her late mother Joanne Siegel to pursue copyright termination. But the appeals court sided with DC, which argued the family had agreed to the settlement and only withdrew from the settlement after attorney Marc Toberoff entered the picture, falsely asserting he had a $15 million offer for the rights from a billionaire investor.
?As the Ninth Circuit noted, it is indeed the case that a ?judgment in DC?s favor on its settlement counterclaim renders moot all of the other questions in this lawsuit,?? DC stated in the motion filed Thursday. ?Her four claims in the Superman case all hinge on the validity of her termination notice and her continued ownership of the allegedly recaptured Superman copyrights. Larson traded any rights she had in Superman to DC, as part of the Oct. 19, 2001, agreement.?
DC has asked for a hearing before U.S. District Judge Otis D. Wright on March 11, the same day he will consider a motion to dismiss the publisher?s copyright-interference claims against Toberoff.
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LOS ANGELES (Reuters) - Daniel Day-Lewis is expected to make Hollywood history by winning his third Best Actor Oscar on February 24 but the public is split over who deserves the Best Supporting Actor prize, a Reuters poll showed on Wednesday.
Day-Lewis, 55, has already picked up almost every major award this season for playing U.S. President Abraham Lincoln in Steven Spielberg's Civil War-era drama "Lincoln" and he is front-runner for the top British BAFTA award on February 10.
A Reuters Ipsos poll of 909 Americans found 21 percent thought British-born Day-Lewis, 55, should win and 26 percent said he was most likely to win Best Actor at the Oscars for Lincoln, a role he assumed both off and on set during filming.
He is up against Hugh Jackman, who came second in the Reuters poll for musical "Les Miserables," Bradley Cooper in the quirky romance "Silver Linings Playbook," Joaquin Phoenix in cult drama "The Master" and Denzel Washington as an alcoholic pilot in "Flight."
If Day-Lewis does win, he will be the first man to take home the Best Actor statue three times, having won the award in 1990 for playing severely disabled Irish artist Christy Brown in "My Left Foot" and in 2008 for his role as oil prospector Daniel Plainview in "There Will be Blood."
But Day-Lewis, who chooses his roles carefully and has only appeared in 10 films in the past 20 years, was not taking a win for granted. It took Spielberg three attempts to persuade him to sign up for the lead role in "Lincoln."
"Members of the Academy love surprises, so about the worst thing that can happen to you is if you've built up an expectation," the actor told reporters after winning the Screen Actors Guild trophy in Los Angeles last week.
Bookmakers, however, were not expecting any surprises, with Day-Lewis the clear favorite to win the Best Actor award.
But the public was less certain on who would bag the award for Best Supporting Actor from the 6,000 members of the Academy of Motion Picture Arts and Sciences.
The field of five includes Alan Arkin from Iran hostage drama "Argo," Robert De Niro as the father in "Silver Linings Playbook," Philip Seymour Hoffman from "The Master," Tommy Lee Jones in "Lincoln," and Christoph Waltz in "Django Unchained."
The results at awards ceremonies so far this year have been mixed.
Jones won at the Screen Actors Guild, Waltz won the Golden Globe, and Seymour Hoffman was chosen Best Supporting Actor at the Critics Choice Movie Awards.
Almost half of the respondents to the online poll, conducted Friday through Tuesday, were unsure who should win at the Oscars in the supporting actor category.
Some 20 percent chose Jones, while 14 percent picked De Niro as the actor most likely to take home the Oscar.
The accuracy of the poll uses a statistical measure called a "credibility interval" and is precise to within 2.8 percentage points.
Bookmakers, however, put 66-year-old Jones as the front-runner to win his second Oscar for his role as liberal congressman Thaddeus Stevens in "Lincoln." He won the Academy Award for Best Supporting Actor in 1994 for "The Fugitive."
(Reporting by Belinda Goldsmith; Editing by Jill Serjeant and Eric Walsh)
Source: http://news.yahoo.com/daniel-day-lewis-likely-win-best-actor-oscar-120247888.html
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As Paul Bedard reports, new information emerges about the man who entered the DC offices of the Family Research Council and opened fire ? a man who would have taken many more lives if the guard had not heroically stopped him:
Floyd Lee Corkins II?pleaded guilty?to three charges including a charge of committing an act of terrorism related to the August 15, 2012 injuring of FRC?s guard. He told the FBI that he wanted to kill anti-gay targets and went to the law center?s website for ideas.
At a court hearing where his comments to the FBI were revealed, he said that he intended to ?kill as many as possible and smear the Chick-Fil-A sandwiches in victims? faces, and kill the guard.? The shooting occurred after an executive with Chick-Fil-A announced his opposition to same-sex marriage.
Read the rest ? including some choice words from FRC President Tony Perkins for the Southern Poverty Law Center.
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Writing for PinkNews.co.uk, political commentator Charlotte Henry analyses the significance of this week?s historic Commons vote on equal marriage.
It?s fairly clear what the consequences for our community will be if, as expected, equal marriage comes to pass. More than being about a wedding, genuine same-sex marriage will mean gay relationships will stop being dismissed as inferior.
Ultimately though this change required politics to make it happen, and many of the consequences will be political too.
For Nick Clegg the situation is, for once, simple. He and Lynne Featherstone will rightly be seen as the driving forces behind this legislation, and receive credit from many for this.
Ed Miliband is also supportive of the legislation, and many of his party followed his lead yesterday. While the Lib Dems may have been the government driving force behind the legislation, it was Labour votes that helped it over the line.
Which brings us on to David Cameron.?The prime minister deserves huge credit for taking on his grassroots and declaring his support at party conference, as well as determinedly making equal marriage part of the coalition?s agenda.
Cameron clearly saw equal marriage as a key part of his modernising agenda, and has the support of a Chancellor who by all accounts is quite liberal on social matters like this.
However, many Tory backbenchers and activists do not share their opinion, and are letting it be known in no uncertain terms.
The sight of grey local association chairman and MPs outside Downing Street petitioning against equal marriage does not help build the image of a modern Conservative Party.
With a significant number of the party?s MPs voting against equal marriage, it shows that many Conservatives have not changed, and this may seriously damage some of Cameron?s compassionate Conservative appeal come 2015.
I suspect that in a matter of a only a few years we will all be quite shocked, and rather embarrassed, by the fraught nature of the political debate around equal marriage. We will question why we ever disputed whether two people who love each other should be able to get married.
Until then, the debate the rumbles on, and political consequences will resonate far away from Westminster.
Charlotte Henry is a writer and consultant in technology, social media, and politics.
She appears in the media discussing issues related to the Liberal Democrats, media and politics.
Her blog can be found here
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Feb. 5, 2013 ? Tourists coming into contact with sea turtles at holiday attractions face a risk of health problems, according to research published February 5 by JRSM Short Reports. Encountering free-living sea turtles in nature is quite safe, but contact with wild-caught and captive-housed sea turtles, typically through handling turtles in confined pools or through consuming turtle products, carries the risk of exposure to toxic contaminants and to zoonotic (animal to human) pathogens such as bacteria, viruses, fungi and parasites. Symptoms, which may take some time to emerge, can resemble gastrointestinal disorders or flu but people more severely affected can suffer septicaemia, pneumonia, meningitis and acute renal failure.
The review included a case study of the Cayman Turtle Farm in Grand Cayman, which between 2007 and 2011 attracted approximately 1.2 million visitors. CTF sells farmed turtle meat to the public and local restaurants. One of the researchers, Clifford Warwick of the Emergent Disease Foundation, said: "The subsequent distribution of visitors exposed to turtle farm conditions may also involve opportunities for further dissemination of contaminants into established tourist hubs including cruise ship and airline carriers."
Warwick added that awareness of potential threats may be modest among health-care professionals and low among the public. "To prevent and control the spreading of sea turtle-related disease, greater awareness is needed among health-care professionals regarding potential pathogens and toxic contaminants from sea turtles, as well as key signs and symptoms of typical illnesses."
The study was funded by the World Society for the Protection of Animals. Warwick said: "Significantly, the captive farming of turtles arguably increases the threat to health, in particular from bacteria, due to the practice of housing many turtles in a relatively confined space and under intensive conditions."
Warwick concluded: "People should avoid food derived from sea turtles and perhaps also other relatively long-lived species regardless of their role in the food chain as all these animals potentially have more time in which to accumulate hazardous organisms and toxins and present an increased risk of animal-linked human pathology."
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/gSwjachZ6JU/130205200235.htm
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Billionaire Warren Buffett gave Berkshire Hathaway stock worth $21.6 million away in the second half of 2012.
Buffett revealed the donations Monday. Buffett, who is Berkshire's chairman and CEO, made donations of Class B shares to four unnamed charities and three individuals between September and December.
The biggest single gift reported Monday was 172,375 shares worth $16.6 million given to a nonprofit.
These gifts are in addition to the 22.4 million Class B Berkshire shares Buffett gave to the Bill & Melinda Gates Foundation and the four Buffett family foundations that are slated to eventually distribute most of Buffett's fortune.
Buffett has said he plans to eventually donate all of his 350,000 Class A and 3.5 million Class B shares of Berkshire stock worth more than $51 billion to charities.
Source: http://www.nbcnews.com/business/buffett-gave-away-21-6-million-late-2012-1B8245442
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Feb. 5, 2013 ? Researchers at Johns Hopkins have devised a way to detect whether cells previously transplanted into a living animal are alive or dead, an innovation they say is likely to speed the development of cell replacement therapies for conditions such as liver failure and type 1 diabetes. As reported in the March issue of Nature Materials, the study used nanoscale pH sensors and magnetic resonance imaging (MRI) machines to tell if liver cells injected into mice survived over time.
"This technology has the potential to turn the human body into less of a black box and tell us if transplanted cells are still alive," says Mike McMahon, Ph.D., an associate professor of radiology at the Johns Hopkins University School of Medicine who oversaw the study. "That information will be invaluable in fine-tuning therapies."
Regenerative medicine advances depend on reliable means of replacing damaged or missing cells, such as injecting pancreatic cells in people with diabetes whose own cells don't make enough insulin. To protect the transplanted cells from the immune system, while allowing the free flow of nutrients and insulin between the cells and the body, they can be encased in squishy hydrogel membranes before transplantation. But, explains McMahon, "once you put the cells in, you really have no idea how long they survive." Such transplanted cells eventually stop working in most patients, who must resume taking insulin. At that point, physicians can only assume that cells have died, but they don't know when or why, says McMahon.
With that problem in mind, McMahon's group, which specializes in methods of detecting chemical changes, collaborated with the research group headed by Jeff Bulte, Ph.D., the director of cellular imaging at Hopkins' Institute for Cell Engineering. Bulte's group devises ways of tracking implanted cells through the body using MRI. Led by research fellow Kannie Chan, Ph.D., the team devised an extremely tiny, or nanoscale, sensor filled with L-arginine, a nutritional supplement that responds chemically to small changes in acidity (pH) caused by the death of nearby cells. Changes in the acidity would in turn set off changes in sensor molecules embedded in the thin layer of fat that makes up the outside of the nanoparticle, giving off a signal that could be detected by MRI.
To test how these nanosensors would work in a living body, the team loaded them into hydrogel spheres along with liver cells -- a potential therapy for patients with liver failure -- and another sensor that gives off bioluminescent light only while the cells are alive. The spheres were injected just under the skin of mice. As confirmed by the light signal, the MRI accurately detected where the cells were in the body and what proportion were still alive. (Such light indicators cannot be used to track cells in humans because our bodies are too large for visible signals to get through, but these indicators allowed the team to check whether the MRI nanosensors were working properly in the mice.)
"It was exciting to see that this works so well in a living body," Chan says. The team hopes that because the components of the system -- hydrogel membrane, fat molecules, and L-arginine -- are safe for humans, adapting their discovery for clinical use will prove relatively straightforward. "This should take a lot of the guesswork out of cell transplantation by letting doctors see whether the cells survive, and if not, when they die," Chan says. "That way they may be able to figure out what's killing the cells, and how to prevent it."
Potential applications of the sensors are not limited to cells inside hydrogel capsules, Bulte notes. "These nanoparticles would work outside capsules, and they could be paired with many different kinds of cells. For example, they may be used to see whether tumor cells are dying in response to chemotherapy," he says.
Other authors on the paper were Guanshu Liu, Xiaolei Song, Heechul Kim, Tao Yu, Dian R. Arifin, Assaf A. Gilad, Justin Hanes, Piotr Walczak and Peter C. M. van Zijl, all of the Johns Hopkins University School of Medicine.
The study was funded by the National Institute of Biomedical Imaging and Bioengineering (grant numbers R01 EB012590, EB015031, EB015032 and EB007825).
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/btuCmMm0qLE/130205123750.htm
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